SIDB
Simons Initiative for the Developing Brain
SIDB
Simons Initiative for the Developing Brain
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    • People
      • Board Members
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      • PhD Students
      • Professional Staff
    • Research
      • Our Approaches
      • Funded Projects
      • Publications
      • Paper Chain Countdown
    • Resources
      • Rat Models
      • Gene Expression
      • LAB-AID
    • Opportunities
      • PhD Studentships
      • Careers
    • Contact
  • Home
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SIDB’s mission is to deliver an integrated and highly collaborative centre, which aims to discover biological mechanisms underlying autism and to use this information to deliver rational therapeutic interventions.

About us

SIDB is a 'virtual' research centre based at the University of Edinburgh, bringing together over 50 principal investigators across 6 research sites. It was founded in 2017, following a generous donation from the Simons Foundation Autism Research Initiative (SFARI). SIDB is a sister centre of the Patrick Wild Centre for Research into Autism, Fragile X Syndrome and Intellectual Disabilities.


SIDB's scientific aims are to:


  • Determine whether there are critical periods during development when treatments are most effective and, if so, whether critical periods are treatment-specific
  • Determine whether genetic convergence predicts convergence of phenotypic pathophysiology and ultimately common treatments
  • Meaningfully stratify autism spectrum disorders based on biological criteria
  • Enable world-class innovative studies into the mechanisms that underlie autism
  • Prepare deep-phenotyped trial-ready cohorts for experimental medicine and clinical trials

 

Our ethos

At SIDB, we believe that there is need for a step-change in autism medicine. There is an absence of effective disease-modifying therapies for autism and other neurodevelopmental disorders, despite decades of research and billions of dollars spent.  


The Centre will promote interaction between clinicians and basic scientists to ensure our research is focused on medically relevant aspects of disease. Integrated fundamental and clinical research programmes are essential to deliver true transformation in translational neuroscience. They must have the explicit objective of improved care for individuals with autism.

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News & events

Patient using a laptop
Patients with Fragile X Syndrome on an iPad
Dr Andrew McKechanie with patient
Dr Andrew McKechanie with patient
Dr Andrew McKechanie with patient
Syngap1 UK family meet up - group photo
SIDB Retreat 2021 Group Photo
Danai Katsanevaki presenting
Ian Duguid presenting
Nathalie Rochefort asking questions at the retreat
Teris Tam
SIDB Retreat at the Secret Herb Garden
Adrian Bird at the Secret Herb Garden
SIDB Retreat at the Secret Herb Garden

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